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This also has more to do with weight changes than the drug itself

Significant nephrotoxic drugs include acetaminophen, NSAIDs, salicylates, aminoglycoside antibiotics, some antiviral drugs, some diabetes medications (GLP-1 agonists), and some chemotherapy drugs

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Not only will dehydration worsen side effects, such as constipation, acute dehydration can significantly harm one's kidneys, especially if he or she is already experiencing the early stages of chronic kidney disease

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Only the needle is changed